Indomethacin
Indomethacin used for the treatment of the pain and inflammation in rheumatoid arthritis and other disorders of muscles or joints.
It is also used to relieve the pain of acute gout and period pains. Indomethacin is available, on prescription only, as capsules,
modified-release capsules or tablets, a suspension, and suppositories.
Side effects: indomethacin commonly causes indigestion, nausea, vomiting, and diarrhoea, gastrointestinal ulceration and bleeding, dizziness, headache, and light-headedness. It may rarely cause drowsiness, confusion, insomnia, psychiatric disturbances, blood disorders, and blurred vision.
Suppositories can cause local irritation and occasionally bleeding.
In addition, indomethacin should be used with caution in people with epilepsy, parkinsonism, or psychiatric illness; suppositories should not be used in people with haemorrhoids. Eye and blood tests are advisable for those taking indomethacin on a long-term basis.
Proprietary preparations: Flexin Continus (modified-release tablets); Imbrilon; Indocid (capsules, sugar-free suspension for children, and suppositories); Indocid-R (modified-release capsules); Indolar SR (modified-release capsules); Indomax; Indomax 75 SR (modified-release capsules); Indomod; Indotard (modified-release capsules); Pardelprin (modified-release capsules); Rheumacin LA (modified-release capsules); Rimacid; Slo-Indo (modified-release capsules).